Search results for "Radiologic sign"

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Staged Reconstruction of Pelvic Ring Disruption: Differences in Morbidity, Mortality, Radiologic Results, and Functional Outcomes Between B1, B2/B3, …

2002

To analyze injury pattern, surgical therapy, radiologic results, and functional outcome in unstable B-type and C-type pelvic ring fractures.Retrospective study.Level I University Trauma Center.Two-hundred-twenty-two consecutive patients, admitted during a nine-year period with unstable B-type (n = 100) and C-type (n = 122) pelvic ring injuries, of whom 122 (61.3 percent of surviving patients) were eligible for evaluation with a minimum follow-up of one year.Staged reconstruction dependent upon injury pattern. Emergency external compression of the pelvic ring in case of hemodynamic instability. Management of associated lesions. Secondary open reduction and internal fracture fixation.Assessme…

Adultmedicine.medical_specialtyAdolescentExternal FixatorsPeriCorrective surgeryFracture Fixation InternalSurgical therapyPostoperative ComplicationsRadiologic signFracture FixationPelvic ringMorbidity mortalitymedicineHumansOrthopedics and Sports MedicineFractures ClosedChildPelvic BonesAgedRetrospective StudiesFixation (histology)Aged 80 and overPelvic girdlebusiness.industryGeneral MedicineMiddle AgedPlastic Surgery ProceduresSurgeryTreatment OutcomeSurgeryMorbiditybusinessJournal of Orthopaedic Trauma
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Thalamic hyperdensity — is it a diagnostic marker for Sandhoff disease?

1993

Sandhoff disease, also known as GM2-gangliosidoses variant 0, is caused by the deficient activity of both hexosaminidase A and hexosaminidase B. We report a 15-month-old boy diagnosed with Sandhoff disease by demonstrating the enzyme deficiency. The interesting finding was bilateral thalamic hyperdensity on the CT scan. The hyperdensity in all previously published cases was homogeneous and symmetric and limited to the thalamus; the cause still remains unknown. We suggest that the finding of dense thalami may be useful as a specific diagnostic criterion for the GM2-gangliosidoses and especially for Sandhoff disease.

MalePathologymedicine.medical_specialtyThalamusSandhoff diseaseGangliosidosisCentral nervous system diseaseHexosaminidase ARadiologic signHexosaminidase BThalamusDevelopmental NeurosciencemedicineHumansHexosaminidasemedicine.diagnostic_testbusiness.industryBrainInfantSandhoff DiseaseMagnetic resonance imagingGeneral Medicinemedicine.diseaseMagnetic Resonance ImagingHexosaminidase Bbeta-N-AcetylhexosaminidasesPediatrics Perinatology and Child HealthNeurology (clinical)Tomography X-Ray ComputedbusinessBrain and Development
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